Turn a BLAST search into interactive species trees, domain clusters and heatmaps — explore presence/absence patterns across whole proteomes and read gene function straight from the data.
Build the species × domain correlation or feature matrix from a BLAST file.
OpenNeighbour-Joining species tree from Jaccard distances between profiles.
OpenCollapsible radial tree — colour by genus, search a species, zoom.
OpenCluster domains (MCL) into an interactive network linked to a co-cluster heatmap.
OpenFeature/correlation heatmaps with ordering, log scale, zoom and cell details.
OpenA plain-language guide for biologists and programmers alike.
ReadPhyloFlask is a software framework for large-scale phylogenetic profile visualization by A. Michailidis, V. S. Papagrigoriou & C. A. Ouzounis (Biological Computation & Computational Biology Group, Artificial Intelligence & Information Analysis Laboratory, School of Informatics, Aristotle University of Thessaloniki).
It analyses presence/absence patterns of protein domains across thousands of reference proteomes to enable rapid, scalable visual inference of gene function and evolutionary relationships — facilitating hypothesis generation for experimental validation.
Reference: Cohen BA, Mitra RD, Hughes JD & Church GM (2000). A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression. Nature Genetics 26(2), 183–186. doi:10.1038/79896